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Top-10 Cat Flea And Tick Preventions
Loved in the USA

Handpicked for quality & trusted by thousands of customers

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Woyamay Fl
Woyamay

Woyamay Flea Treatment for Cats, 200 Treats Flea and Tick Prevention for Cats Chewables, Natural Cat Flea and Tick Treatment Pills Daily Oral Flea Supplement, Kitten Cat Flea Treatment, Chicken Flavor

#1
Top Rated in the USA
Advantage
Advantage

Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 2-Month Supply

Fast Delivery
10.0
74 895 reviews

Solid Value from a Trusted Brand

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1 379 bought in past month

Sponsored

Woyamay Fl
Woyamay

Woyamay Flea Treatment for Cats, 200 Treats Flea and Tick Prevention for Cats Chewables, Natural Cat Flea and Tick Treatment Pills Daily Oral Flea Supplement, Kitten Cat Flea Treatment, Chicken Flavor

#2
PetArmor P
PetArmor

PetArmor Plus Flea and Tick Prevention for Cats, Cat Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting, Cats Over 1.5 lbs

19%OFF

Fast Delivery
10.0
4 477 reviews

Item still has Pre-Tariff price

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1 277 bought in past month
Last Purchases
Th***as
Phoenix, AZ
4d ago
B***n
Miami, FL
4d ago
B***n
Philadelphia, PA
1d ago
#3
Frontline
Frontline

Frontline Plus Flea and Tick Treatment for Cats Over 1.5 lbs. 3 Treatments

11%OFF

Fast Delivery
10.0
47 552 reviews

Item still has Pre-Tariff price

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1 175 bought in past month
Premium quality and flawless performance. My best purchase, worth every penny!
JessyChicago, IL
#4
Seresto La
Seresto

Seresto Large Dog Vet-Recommended Flea & Tick Treatment & Prevention Collar for Dogs Over 18 lbs. | 2-Pack

Fast Delivery
9.9
108 393 reviews

Solid Value from a Trusted Brand

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1 073 bought in past month
Curated products trusted bytrust us brands
#5
Seresto Ca
Seresto

Seresto Cat Vet-Recommended Flea & Tick Treatment & Prevention Collar for Cats, 8 Months Protection | (Pack of 2)

Fast Delivery
9.8
42 307 reviews

Solid Value from a Trusted Brand

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971 bought in past month
#6
Advantage
Advantage

Advantage II Small Cat Vet-Recommended Flea Treatment & Prevention | Cats 5-9 lbs. | 6-Month Supply

Fast Delivery
9.6
37 134 reviews

Solid Value from a Trusted Brand

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869 bought in past month
#7
CAPSTAR (n
Capstar

CAPSTAR (nitenpyram) Oral Flea Treatment for Cats, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Cats 2-25 lbs, 6 Doses

Fast Delivery
9.4
38 219 reviews

Solid Value from a Trusted Brand

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767 bought in past month
#8
PetArmor C
PetArmor

PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Cats, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Cats 2-25 lbs, 6 Doses

Fast Delivery
9.1
16 163 reviews

Solid Value from a Trusted Brand

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665 bought in past month
#9
TevraPet F
TevraPet

TevraPet FirstAct Plus Flea and Tick Prevention for Cats Over 1.5lbs, 6 Monthly Doses, Topical Drops

Fast Delivery
8.8
13 316 reviews

Solid Value from a Trusted Brand

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563 bought in past month
#10
NEXTSTAR F
NEXTSTAR

NEXTSTAR Flea and Tick Prevention for Cats, Repellent, and Control, Fast Acting Waterproof Topical Drops for Cats Over 3.5 lbs, 3 Month Dose

Fast Delivery
8.6
1 051 reviews

Solid Value from a Trusted Brand

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461 bought in past month

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TevraPet A
TevraPet

TevraPet Actispot II Flea Treatment for Large Cats 9+ lbs | 6 Doses | Powerful Prevention and Control

Fast Delivery
17 453
verified reviews

Solid Value from a Trusted Brand

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359 bought in past month
Catego for
Catego

Catego for Cats Flea and Tick Treatment & Prevention (Over 1.5 lbs) 6-Month Supply

Fast Delivery
5 755
verified reviews

Solid Value from a Trusted Brand

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257 bought in past month
Advantage
Advantage

Advantage XD Large Cat Flea Prevention & Treatment For Cats over 9lbs. | 1-Topical Dose, 2-Months of Protection Per Dose

Fast Delivery
2 323
verified reviews

Solid Value from a Trusted Brand

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155 bought in past month
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Revolution
Revolution Plus

Revolution Plus (selamectin and sarolaner Topical Solution) for Cats, 11.1-22 lbs (Green), 6 Tubes

Fast Delivery
26
verified reviews

Solid Value from a Trusted Brand

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53 bought in past month
Advantage
Advantage

Advantage XD Small Cat Flea Prevention & Treatment For Cats 1.8-9lbs. | 1-Topical Dose, 2-Months of Protection Per Dose

Fast Delivery
1 539
verified reviews

Solid Value from a Trusted Brand

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Our Top Picks

#1

Winner

Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 2-Month Supply

Rating
10.0
Chosen by1,379
Side Effects and Safety
Ease of Application

Most important from
74895 reviews

Side Effects and Safety
Excellent product, really works and doesn’t bother our cat at all.
Ease of Application
Fleas be gone! Easy to use and not as expensive as other products.

Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention is specifically designed for large cats over 9 lbs and at least 8 weeks old. This product stands out as an easy-to-apply monthly topical treatment that eliminates the need for hard-to-swallow pills and does not require a prescription. It's effective against adult fleas, flea larvae, and flea eggs, providing comprehensive protection.

The treatment starts working within 12 hours of application and remains effective for 30 days, ensuring continuous flea control for a month. Additionally, it is fragrance-free and waterproof, making it suitable for cats' daily activities after 24 hours of application. The active ingredients, Imidacloprid and Pyriproxyfen, are known for their efficacy in flea control.

It is crucial to follow the application instructions carefully to avoid any adverse effects, such as getting the product in the cat's eyes or ingestion. While the product is generally safe, some cats might experience mild side effects like skin irritation. The ease of application is greatly appreciated by pet owners, as it simplifies the process of flea prevention. This product is highly recommended for large cats who need reliable and effective flea treatment without the hassle of pills.

Rating
10.0
Chosen by1,379
Side Effects and Safety
Ease of Application

Most important from
74895 reviews

Side Effects and Safety
Excellent product, really works and doesn’t bother our cat at all.
Ease of Application
Fleas be gone! Easy to use and not as expensive as other products.
#2

PetArmor Plus Flea and Tick Prevention for Cats, Cat Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting, Cats Over 1.5 lbs

Rating
10.0
Type of Prevention
Duration of Effectiveness
Side Effects and Safety

Most important from
4477 reviews

Type of Prevention
The treatment helps break the flea life cycle by targeting eggs and larvae, reducing chances of re-infestation.
Duration of Effectiveness
The formula starts working quickly, offering protection that lasts up to a month.
Side Effects and Safety
Consistent use prevents flea infestations effectively without causing any side effects.
Ease of Application
Applying the treatment is hassle-free, with cats remaining calm and not distressed during application.

PetArmor Plus Flea and Tick Prevention for Cats is a topical treatment designed to protect cats over 1.5 pounds and older than 8 weeks from fleas, ticks, and chewing lice. It uses active ingredients fipronil and (S)-methoprene, which are the same found in popular vet-recommended brands, making it a trusted formula. The treatment is waterproof and starts killing fleas within 24 hours, continuing to work for up to 30 days. One of its strengths is that it not only kills adult fleas but also targets flea eggs and larvae, helping to break the flea life cycle and reduce the chance of re-infestation. The product comes in a pack of three monthly doses, providing up to three months of protection.

Applying the drops is straightforward: you part the cat’s fur between the shoulder blades and squeeze the solution onto the skin. However, some cats may have greasy fur around the application site for up to two days. The treatment is generally safe if instructions are followed, but it’s important to keep treated cats away from other pets and children until the product dries.

This product is effective and easy to use but requires careful handling to avoid excess residue. Users should watch for any adverse reactions, although none are commonly reported. This solution fits well for cat owners looking for an affordable, vet-quality, monthly flea and tick prevention that is simple to apply and effective at breaking the flea cycle.

Rating
10.0
Type of Prevention
Duration of Effectiveness
Side Effects and Safety

Most important from
4477 reviews

Type of Prevention
The treatment helps break the flea life cycle by targeting eggs and larvae, reducing chances of re-infestation.
Duration of Effectiveness
The formula starts working quickly, offering protection that lasts up to a month.
Side Effects and Safety
Consistent use prevents flea infestations effectively without causing any side effects.
Ease of Application
Applying the treatment is hassle-free, with cats remaining calm and not distressed during application.
#3

Frontline Plus Flea and Tick Treatment for Cats Over 1.5 lbs. 3 Treatments

Rating
10.0
Type of Prevention
Duration of Effectiveness
Side Effects and Safety

Most important from
47552 reviews

Type of Prevention
Using Frontline Plus regularly not only prevents fleas but also helps avoid more serious conditions like tapeworms, roundworms, and heartworms.
Duration of Effectiveness
Frontline Plus is highly effective when applied correctly every 30 days, ensuring cats remain flea and parasite free.
Side Effects and Safety
The product works wonders for both indoor and outdoor cats, keeping them free from fleas and ticks without any side effects or irritation.
Ease of Application
Applying the product at the base of the neck instead of between the shoulder blades makes it easier and more comfortable for the cat.

FRONTLINE Plus Flea and Tick Treatment for Cats is designed for cats weighing over 1.5 lbs and older than eight weeks. It is a waterproof and fast-acting solution that kills fleas, flea eggs, flea larvae, chewing lice, and ticks, including those that can transmit Lyme disease. The active ingredients, fipronil and (S)-methoprene, work together to break the flea life cycle and provide protection for up to 30 days with a single application.

This makes it a long-lasting option for pet owners looking to control infestations and prevent new ones from starting. The treatment is applied topically, which might require some effort to ensure it reaches the skin and not just the fur, but it is generally considered easy to use with clear instructions provided. However, care must be taken to avoid applying it to cats under 1.5 lbs or younger than eight weeks due to potential safety concerns.

Some users have reported side effects like temporary skin irritation at the application site, so monitoring your pet after application is recommended. Despite these minor drawbacks, FRONTLINE Plus has been trusted by pet owners for over 20 years and boasts a solid reputation. It is an excellent choice for those seeking a reliable and effective flea and tick prevention method for their cats.

Rating
10.0
Type of Prevention
Duration of Effectiveness
Side Effects and Safety

Most important from
47552 reviews

Type of Prevention
Using Frontline Plus regularly not only prevents fleas but also helps avoid more serious conditions like tapeworms, roundworms, and heartworms.
Duration of Effectiveness
Frontline Plus is highly effective when applied correctly every 30 days, ensuring cats remain flea and parasite free.
Side Effects and Safety
The product works wonders for both indoor and outdoor cats, keeping them free from fleas and ticks without any side effects or irritation.
Ease of Application
Applying the product at the base of the neck instead of between the shoulder blades makes it easier and more comfortable for the cat.

Buying Guide for the Best Cat Flea And Tick Preventions

Choosing the right flea and tick prevention for your cat is crucial for their health and comfort. Fleas and ticks can cause a range of issues from mild irritation to serious diseases. When selecting a product, consider your cat's lifestyle, health status, and any specific needs they may have. It's important to understand the different types of preventions available and how they work to make an informed decision that best suits your cat's needs.
Type of PreventionFlea and tick preventions come in various forms such as topical treatments, oral medications, collars, and shampoos. Topical treatments are applied directly to the cat's skin and are effective for a month. Oral medications are ingested and can provide protection for up to three months. Collars release active ingredients over time and can last for several months. Shampoos provide immediate relief but need to be used regularly. Choose the type based on your cat's tolerance and your convenience.
Active IngredientsThe active ingredients in flea and tick preventions are what kill or repel the pests. Common ingredients include fipronil, imidacloprid, and fluralaner. Each ingredient works differently and may target different stages of the flea or tick lifecycle. It's important to choose a product with ingredients that are safe for cats and effective against the specific pests in your area. Consult your vet to determine which active ingredients are best for your cat.
Duration of EffectivenessThe duration of effectiveness refers to how long the prevention will protect your cat from fleas and ticks. This can range from a few days with shampoos to several months with collars. Consider how often you are willing to reapply or administer the prevention. For busy pet owners, longer-lasting options like collars or oral medications might be more convenient.
Age and Weight RestrictionsMany flea and tick preventions have age and weight restrictions to ensure safety and effectiveness. Products are often formulated for specific age groups, such as kittens or adult cats, and weight ranges. Always check the product label to ensure it is appropriate for your cat's age and weight. Using a product not suited for your cat can lead to ineffective treatment or potential health risks.
Side Effects and SafetyAll flea and tick preventions have the potential for side effects, which can range from mild skin irritation to more serious reactions. It's important to read the product label and consult with your vet about any potential side effects, especially if your cat has a history of allergies or sensitivities. Choose a product with a good safety profile and monitor your cat for any adverse reactions after application.
Ease of ApplicationThe ease of application can vary significantly between different types of flea and tick preventions. Topical treatments and collars are generally easy to apply, while oral medications may require more effort if your cat is resistant to taking pills. Shampoos require regular bathing, which can be challenging if your cat dislikes water. Consider your cat's temperament and your ability to administer the treatment when choosing a product.

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